Tsc2 cst
WebJul 12, 2024 · Tuberous Sclerosis Complex (TSC) is caused by TSC1 or TSC2 mutations, resulting in hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1). …
Tsc2 cst
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WebPolyclonal Antibody for studying Tuberin/TSC2 (Thr1462) phosphate. Cited in 59 publications. Validated for Western Blotting. Highly specific and rigorously validated in … WebWe also demonstrate TSC mutations in a case of so-called "oncocytoid RCC after neuroblastoma" with identical morphology and immunoprofile, providing a molecular link between the latter and ESC RCC. In summary, ESC RCC consistently harbors actionable TSC1 or TSC2 mutations, which are infrequently seen in established subtypes of RCC.
WebFeb 4, 2024 · Protein lysates were separated by 4 to 12% bis-tris gels (Invitrogen) and then transferred to a polyvinylidene difluoride membrane. After the membranes were blocked, … WebThe TSC2 gene provides instructions for producing a protein called tuberin. Within cells, tuberin interacts with a protein called hamartin, which is produced from the TSC1 gene. These two proteins help control cell growth and division (proliferation) and cell size. Proteins that normally prevent cells from growing and dividing too fast or in an ...
Web1.1.2 主要试剂：DMEM-高糖培养基(Corning公司)；胎牛血清和EDTA-0.25% 胰蛋白酶(Gibco公司)；噻唑蓝(MTT)和二甲基亚砜(DMSO)(Ameresco公司)；氢氧化钠(NaOH)(北京化工厂)；雷帕霉素(rapamycin，Rapa)和羟乙基哌嗪乙硫磺酸(HEPES)(Sigma-Aldrich公司)；多聚甲醛和结晶紫(武汉塞维尔公司)；细胞周期与细胞凋亡检测试剂盒 ... WebAug 24, 2012 · The tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 complex, which limits cell growth in response to poor growth conditions. Through …
WebPolyclonal Antibody for studying Tuberin/TSC2. Cited in 82 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Tuberin/TSC2 …
WebJun 28, 2024 · To evaluate the knockdown efficiency of siRNA-TSC2 at the level of TSC2, high glucose-cultured podocytes were transfected with three different siRNA-TSC2 sequences. After TSC2 siRNA treatment for 24 h, Western blot analysis showed that transfection of TSC2 siRNA-1, TSC2 siRNA-2, and TSC2 siRNA-3 significantly reduced the … shap stonesWebResponsável pelo serviço de impressão, gestão da fila de chamados com atuação nas ferramentas Service-now e Tsc2, comprometimento na resolução dos chamados internos e externos, cumprimento dos prazos estabelecidos, SLA, análise de faturamento, boas práticas do uso de Toner, manutenção corretiva e preventiva das multifuncionais P&B e … pooh shiesty incarceratedWebMay 17, 2024 · Loss-of-function mutations in TSC1 or TSC2, but not TBC1D7, give rise to TSC, a pleiotropic disorder with aberrant ... CST #5425) was used as a blocking solution … shap summary plot explanationWebApr 25, 2008 · AMPK phosphorylation of the TSC2 tumor suppressor contributes to suppression of mTORC1; however, TSC2-deficient cells remain responsive to energy stress. Using a proteomic and bioinformatics approach, we sought to identify additional substrates of AMPK that mediate its effects on growth control. pooh shiesty in jail forWebMay 17, 2024 · Loss-of-function mutations in TSC1 or TSC2, but not TBC1D7, give rise to TSC, a pleiotropic disorder with aberrant ... CST #5425) was used as a blocking solution for 1 h at room temperature. Primary antibodies, p(S235/236)S6 (CST #4858, 1:400), fast skeletal Myosin (Sigma #M4276, 1:400), and slow skeletal Myosin (Abcam # ... pooh shiesty jail pictureWebFor immunoprecipitation of endogenous TSC and mTOR complexes, cell lysates were incubated with TSC2 antibody (CST, 4308) or mTOR antibody (CST, 2972) at 4oC with rocking for 4 hours, followed by an additional 2 hour incubation with 30µl of 50% slurry A/G-agarose beads (Thermo Scientific/Pierce, 20421). shap summary plot class namesWebMonoclonal Antibody for studying Raptor. Cited in 516 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously … shap summary plot color bar