WebJan 28, 2024 · The direct effects of ionizing radiation can include: 1) Changing the chemistry of a nucleotide 2) Breaking the sugar-phosphate backbone and 3) Breaking hydrogen bonds between bases (Let’s Talk Science using an image by Dosto [CC BY-SA 3.0] via Wikimedia Commons ). Direct action can lead to either DNA damage or DNA mutations. WebJun 12, 2024 · Hürthle cell carcinoma (HCC) is a recurrent subtype of non-medullary thyroid cancer. HCC is characterized by profound whole-chromosome instability (w-CIN), resulting in a near-homozygous genome (NHG), a phenomenon recently attributed to reactive oxygen species (ROS) generated during mitosis by malfunctioning mitochondria.
Hürthle cells in fine‐needle aspirates of the thyroid: A review of ...
WebJan 16, 2014 · What Are Hürthle Cells? By light microscopy, Hürthle cells refer to modified follicular cells exhibiting abundant finely granular cytoplasm, a round nucleus, and a variably conspicuous nucleolus. Although their cytoplasm appears eosinophilic (oxyphilic, oncocytic) on H&E stain, it can be orangish, greenish, or bluish on Papanicolaou-stained slides. WebMar 1, 2024 · Treatment for Hurthle cell cancer usually involves surgery to remove the thyroid. Other treatments may be recommended, depending on your situation. Surgery Parathyroid glands Total or near-total removal of the thyroid (thyroidectomy) is the most common treatment for Hurthle cell cancer. imgtown 7388
Hurthle Cell Cancer Overview - Thyroid Cancer Center
WebOncocytic follicular cells in the thyroid, known as Hürthle cells, are characterised by large size, polygonal to square shape, distinct cell borders, voluminous granular and … WebFocal nuclear atypia in cyst-lining or follicular cells and a monotonous population of macrophages misinterpreted as Hurthle cells (HCs) were the causes of IEs in this category. WebJan 20, 2005 · Epithelioid cyst lining cells, like Hürthle cells, are polygonal cells with abundant dense, granular, eosinophilic cytoplasm, finely dispersed chromatin, and distinct nucleoli. Both Hürthle cells and cyst-lining cells … imgtown 6600