Irf3 mouse
WebFeb 4, 2013 · Red - loading control ab8245 (Mouse anti-GAPDH antibody [6C5]) observed at 37kDa. ab76409 was shown to react with IRF3 in wild-type A549 cells in western blot with loss of signal observed in IRF3 knockout cell line ab267097 (IRF3 knockout cell lysate ab256953). Wild-type and IRF3 knockout A549 cell lysates were subjected to SDS-PAGE. WebApr 11, 2024 · For mouse studies with IFNAR antibody treatment, following streptomycin treatment as described above, mice were injected intraperitoneally with 250 µg of isotype control (In vivo Mouse IgG1 ...
Irf3 mouse
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WebOct 15, 2013 · Double-deficient Irf-3(-/-)7(-/-) mice infected with the DENV2 strain S221 possessed 1,000-150,000 fold higher levels of viral RNA than wild-type and single-deficient mice 24 h postinfection (hpi); however, they remained resistant to lethal infection. WebMay 5, 2024 · The nuclear translocation of activated IRF3 leads to the transcriptional upregulation of type I interferons and pro-inflammatory cytokines 2, 19, 20. An essential role for cGAS is its capacity to...
WebMar 9, 2024 · Irf3 interferon regulatory factor 3 [ Mus musculus (house mouse) ] Gene ID: 54131, updated on 9-Mar-2024 Download Datasets Summary Official Symbol Irf3 provided … WebWe previously showed that interferon regulatory factor 3 (IRF3) contributes to sepsis pathogenesis in young mice subject to cecal ligation and puncture (CLP). In this study, we investigated if IRF3 contributes to sepsis in the context of aging. ... Two-way repeated measures ANOVA was used to compare the mouse surface temperature and disease ...
WebIrf3 Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > … WebMar 4, 2024 · We next examined the endogenous association between IRF3 and USP22, and immunoblot analysis revealed that USP22 interacted with IRF3 in mouse bone marrow–derived dendritic cells (BMDCs) and MEFs after SeV or HSV-1 infection . USP22 has been reported to be localized in cytoplasm and nucleoplasm (Xiong et al., 2014).
WebIrf3 MGI Mouse Gene Detail - MGI:1859179 - interferon regulatory factor 3 Home Genes Phenotypes Human Disease Expression Recombinases Function Strains / SNPs Homology Tumors About Help FAQ Search All Search Tools Genes Genes & Markers Query Batch Query JBrowse Genome Browser Multiple Genome Viewer (MGV) More Phenotypes
WebNov 1, 2012 · IFN regulatory factor 3 (IRF3) regulates early type I IFNs and other genes involved in innate immunity. We have previously shown that cells undergoing an endoplasmic reticulum (ER) stress response called the unfolded protein response produce synergistically augmented IFN-β when stimulated with pattern recognition receptor … the pointe apartments stafford vaWebIrf3 MGI Mouse Gene Detail - MGI:1859179 - interferon regulatory factor 3 Search Submit Data Find Mice (IMSR) Analysis Tools Contact Us Browsers Irf3 Gene Detail Summary … sidewinder chat friesWebImmunogen Synthetic peptide within Human IRF3 aa 50-150. The exact sequence is proprietary. Database link: Q14653 (Peptide available as ab203561) Positive control WB: A549, HeLa, Jurkat, THP-1, Daudi, HepG2 whole cell lysates. Human fetal heart and kidney lysates. Mouse heart and spleen lysates, NIH/3T3 whole cell lysates. the pointe apartments siuWebIRF3 Antibodies. Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry … the pointe apartments west chester paWebJan 24, 2024 · Three-prime repair exonuclease 1 knockout (Trex1 -/-) mice suffer from systemic inflammation caused largely by chronic activation of the cyclic GMP-AMP synthase-stimulator of interferon genes-TANK-binding kinase-interferon regulatory factor 3 (cGAS-STING-TBK1-IRF3) signaling pathway. sidewinder coffeeWebFlow cytometric analysis of adipocytes from wild type mice, untransfected (A) or transfected with Poly (I:C) (2.5 µg/ml, 6 hr; B), and adipocytes from IRF-3 (-/-) mice, untransfected (C) or transfected with Poly (I:C) (2.5 µg/ml, 6 hr; D), using Phospho-IRF … sidewinder coasterIRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found … the point eastbourne