Ctsh protein
WebProteome-wide association studies (PWASs) of AD found that variants rs12148472 and rs34593439 in the CTSH gene were associated with the CTSH protein abundance in human brain tissues [9, 33,34 ... WebThe cytoskeletal protein talin, an actin- and β-integrin tail-binding protein, plays an important role in cell migration by promoting integrin activation and focal adhesion formation. Here, we show that talin is a substrate for cathepsin H (CtsH), a lysosomal cysteine protease with a strong aminopeptidase activity. Purified active CtsH sequentially cleaved …
Ctsh protein
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WebConsistent with extensive gene/protein characterization data. Consistent with extensive gene/protein characterization data. RNA consistency i High consistency between antibody staining and RNA expression data. High consistency between antibody staining and RNA expression data. ... CTSH-201. CTSH-207. CTSH-218. CTSH-232. CTSH-233. CTSH … WebCTSH; cathepsin H; Description From CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal …
WebNM_004390.5(CTSH):c.785A>G (p.Tyr262Cys) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Dec 21, 2024) Review status: 1 star out of maximum of 4 stars WebApr 20, 2024 · Ctsh protein seemed decreased in EA lungs compared with age-matched control. (C,D) Representative immunoblotting and densitometric analysis of Bmp4 and Ctsh protein expression in fetal …
WebThe protein expression overview (Figure 7B) suggested that higher expression appeared in prostate cancer, thyroid cancer and renal cancer. Among human cancers, both mRNA … WebImportant for the overall degradation of proteins in lysosomes. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase …
WebCathepsin H (CTSH) is a type 1 diabetes (T1D) risk gene; large-scale genetic and epidemiological studies found that T1D genetic risk correlates with high CTSH …
WebInterestingly, the CTSH protein expression data support the clinical observation that the TT genotype differs from the CC and CT genotypes. The lack of association between CTSH … can heart problems cause migrainesWebFurthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2 e,i,j). From this perspective, we found a novel ... fit father diet planfit father meal plan reviewWebCTSH. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide … can heart problems cause panic attacksWebNM_004390.5(CTSH):c.296C>T (p.Pro99Leu) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Nov 29, 2024) Review status: 1 star out of maximum of 4 stars fit father free meal planWebCTSH: Pro-cathepsin H; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family (335 aa) ... Pulmonary surfactant-associated protein … fit father band workoutWebJan 30, 2024 · Another type 1 diabetes susceptibility gene, Cathepsin H (CTSH) [36, 37], is a lysosomal cysteine protease that is crucial for lysosomal protein degradation. Importantly, the CTSH susceptibility allele is associated with faster disease progression in newly diagnosed diabetes and reduced beta cell function in healthy humans . fit father meal plan