WebApr 1, 2024 · HyTs based on the large Boc3Arg group are similarly described, with the first being exemplified to target gluthathione-S-transferase (GST) by attachment to ethacrynic … WebBoc3Arg-Linked Ligands Induce Degradation by Localizing Target Proteins to the 20S Proteasome. Journal content Created on Oct 18, 2016 by ACS Chemical Biology. Details ; All journal content; My journal content
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WebÿØÿî AdobedÀ ÿÛ„ ÿÀ € ÿÄØ # ! WebApr 1, 2015 · Degradation Mechanism of Boc3Arg Mediated Degradation Authors: Yuntao Shi Brandeis University Marcus Long Aimee Kobjack Shican Li Show all 5 authors Request full-text 20+ million members 135+... how do elections endanger democracy
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WebBoc3Arg-Linked Ligands Induce Degradation by Localizing Target Proteins to the 20S Proteasome; Bioluminescent Protein–Inhibitor Pair in the Design of a Molecular Aptamer Beacon Biosensing System; The Development of a Facile Tandem Wolff/Cope Rearrangement for the Synthesis of Fused Carbocyclic Skeletons WebShi, Y., Long, M. J. C., Rosenberg, M. M., Li, S., Kobjack, A., Lessans, P., … Hedstrom, L. (2016). Boc3Arg-Linked Ligands Induce Degradation by Localizing Target ... Web(AID),11 Boc3Arg12 and phthalimide conjugations13 and hydro-phobic tagging.14 These approaches have been successfully applied to degrade many important proteins.15 Studies showed that thehydrophobic groupof the misfolded protein is exposed to its surface, which can be recognized and degraded by the ubiquitin–proteasome system (UPS).12 Based how much is gold worth jailbreak